Tag: SOP for Pharmacokinetics

SOP for Using Computational Tools for Target Pathway Analysis

SOP for Using Computational Tools for Target Pathway Analysis Standard Operating Procedure (SOP) for Using Computational Tools for Target Pathway Analysis 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to outline the use of computational tools in the analysis of target pathways during drug discovery. Understanding the molecular pathways and interactions involved…

Drug Discovery

SOP for High-Content Screening Methods

SOP for High-Content Screening Methods Standard Operating Procedure (SOP) for High-Content Screening Methods 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to outline the process for conducting high-content screening (HCS) methods in drug discovery. HCS is a powerful technique that allows for the simultaneous measurement of multiple cellular events, providing comprehensive insights…

Drug Discovery

SOP for Screening Enzyme Inhibitors

SOP for Screening Enzyme Inhibitors Standard Operating Procedure (SOP) for Screening Enzyme Inhibitors 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to outline the process for screening enzyme inhibitors in drug discovery. Enzyme inhibitors are crucial tools in developing therapeutic agents for diseases where enzymes play a key role in disease progression….

Drug Discovery

SOP for Early-Stage Biomarker Identification

SOP for Early-Stage Biomarker Identification Standard Operating Procedure (SOP) for Early-Stage Biomarker Identification 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the process of identifying early-stage biomarkers in drug discovery. Biomarkers are biological molecules or indicators that provide insight into disease progression, drug efficacy, and safety. Early-stage biomarker identification plays…

Drug Discovery

SOP for Preclinical Efficacy Studies Using Cell Lines

SOP for Preclinical Efficacy Studies Using Cell Lines Standard Operating Procedure (SOP) for Preclinical Efficacy Studies Using Cell Lines 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to outline the process for conducting preclinical efficacy studies using cell lines in drug development. Preclinical efficacy studies assess the biological activity and potential therapeutic…

Drug Discovery

SOP for Preparing Target Binding Affinity Reports

SOP for Preparing Target Binding Affinity Reports Standard Operating Procedure (SOP) for Preparing Target Binding Affinity Reports 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to define the process of preparing binding affinity reports for drug discovery studies. Binding affinity reports provide critical information on the strength and specificity of interactions between…

Drug Discovery

SOP for Molecular Dynamics Simulations

SOP for Molecular Dynamics Simulations Standard Operating Procedure (SOP) for Molecular Dynamics Simulations 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to outline the procedure for performing Molecular Dynamics (MD) simulations in drug discovery. MD simulations provide a detailed, time-resolved view of molecular motion, helping to understand protein-ligand interactions, stability, conformational changes,…

Drug Discovery

SOP for Cryo-EM Studies in Drug Development

SOP for Cryo-EM Studies in Drug Development Standard Operating Procedure (SOP) for Cryo-EM Studies in Drug Development 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the process of using Cryo-Electron Microscopy (Cryo-EM) for studying biomolecular structures in drug development. Cryo-EM is a powerful technique for determining the three-dimensional structures of…

Drug Discovery

SOP for NMR Spectroscopy for Structure Elucidation

SOP for NMR Spectroscopy for Structure Elucidation Standard Operating Procedure (SOP) for NMR Spectroscopy for Structure Elucidation 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the process of using Nuclear Magnetic Resonance (NMR) spectroscopy to determine the three-dimensional structure of biomolecules and drug candidates in solution. NMR spectroscopy is a…

Drug Discovery

SOP for X-Ray Crystallography in Drug Discovery

SOP for X-Ray Crystallography in Drug Discovery Standard Operating Procedure (SOP) for X-Ray Crystallography in Drug Discovery 1) Purpose The purpose of this Standard Operating Procedure (SOP) is to describe the process of using X-ray crystallography for determining the three-dimensional structure of biomolecules, such as proteins, nucleic acids, and their complexes with drug candidates. X-ray…

Drug Discovery