Skip to content
  • Clinical Studies
  • Schedule M
  • Stability Studies
  • Pharma GMP
  • Pharma Tips
  • Pharma Books
  • Pharma Validation
  • Pharma Regulatory

SOP Guide for Pharma

The Ultimate Resource for Pharmaceutical SOPs and Best Practices

  • Home
  • Job Safety Analysis (JSA)
    • Oral Dosage Forms (Tablets & Capsules)
    • Oral Liquid Dosage Forms (Syrups, Elixirs, Suspensions, Emulsions)
    • Powder and Granule Dosage Forms
    • Topical Dosage Forms (Creams, Ointments, Gels, Lotions, Pastes)
    • Transdermal Dosage Forms (Patches)
  • Standard Test Procedures (STP)
  • SOP – Blog Post
  • Toggle search form

SOP for Cream Emulsifier

Posted on By

SOP for Cream Emulsifier

Operation and Maintenance of Cream Emulsifier

1) Purpose

The purpose of this SOP is to outline the procedures for operating and maintaining the cream emulsifier to ensure efficient emulsification of cream formulations.

2) Scope

This SOP applies to all personnel involved in the operation, cleaning, and maintenance of the cream emulsifier in the manufacturing facility.

3) Responsibilities

It is the responsibility of production operators, maintenance staff, and quality control personnel to follow this SOP to ensure proper operation and maintenance of the cream emulsifier.

4) Procedure

4.1 Preparation

  1. Ensure the work area and equipment are clean and sanitized before starting the emulsification process.
  2. Verify the availability and integrity of cream formulation ingredients.
  3. Inspect the cream emulsifier, including mixing blades and temperature control systems, to ensure they are clean and operational.
See also  SOP for Ring Forming Machine

4.2 Emulsification Process

  1. Set up the emulsification parameters such as mixing speed, temperature, and emulsifier addition rate according to the formulation requirements.
  2. Load the ingredients into the emulsifier and start the mixing process.
  3. Monitor the emulsification process to achieve the desired cream consistency and uniform distribution of ingredients.

4.3 Cleaning and Maintenance

  1. Stop the cream emulsifier after completing the emulsification batch.
  2. Disassemble mixing blades and clean them thoroughly using appropriate cleaning agents.
  3. Perform routine maintenance tasks such as lubrication of moving parts and inspection of seals.

5)

Abbreviations, if any

N/A

6) Documents, if any

Batch production record, Cleaning log, Cream formulation record

7) Reference, if any

GMP guidelines, Manufacturer’s operating manual for cream emulsifier

8) SOP Version

Version 1.0

Vaginal Dosage Forms Tags:Audit trail SOP for vaginal dosage forms, Batch record review SOP for vaginal formulations, Batch release procedure for vaginal gels, Change control SOP for vaginal products, Cleaning validation SOP for vaginal equipment, Complaint handling SOP for vaginal products, Deviation handling SOP for vaginal dosage forms, Documentation control SOP for vaginal SOPs, environmental monitoring in vaginal manufacturing, Filling suppositories, GMP SOP for vaginal gel manufacturing, Labeling SOP for vaginal medicines, Mixing SOP for vaginal formulations, Packaging SOP for vaginal dosage forms, Procedure for vaginal ring production, Process validation SOP for vaginal preparations, Quality control SOP for vaginal tablets, Risk assessment SOP for vaginal manufacturing, SOP for emergency response in vaginal production, SOP for filling vaginal suppositories, SOP for vaginal cream formulation, SOP for vaginal dosage forms, SOP for vaginal medications, SOP for vaginal production, Stability testing SOP for vaginal rings, Sterility testing SOP for vaginal products, Suppository SOP, Training program for vaginal product manufacturing, Vaginal suppository manufacturing SOP, Vaginal tablet production guidelines, Validation protocol for vaginal creams, Vendor qualification SOP for vaginal ingredients

Post navigation

Previous Post: SOP for Sterility Testing in Aseptic Transdermal Patches
Next Post: SOP for Preventing Contamination in Lotions Production

Standard Operating Procedures V 1.0

  • Aerosols
  • Analytical Method Development
  • Bioequivalence Bioavailability Study
  • Capsule Formulation
  • Clinical Studies
  • Creams
  • Data Integrity
  • Dental Dosage Forms
  • Drug Discovery
  • Environment, Health and Safety
  • Formulation Development
  • Gels
  • Good Distribution Practice
  • Good Warehousing Practices
  • In-Process Control
  • Injectables
  • Liquid Orals
  • Liposome and Emulsion Formulations
  • Lotions
  • Lyophilized Products
  • Maintenance Dept.
  • Medical Devices
  • Metered-Dose Inhaler
  • Microbiology Testing
  • Nanoparticle Formulation
  • Nasal Spray Formulations
  • Nebulizers
  • Ocular (Eye) Dosage Forms
  • Ointments
  • Otic (Ear) Dosage Forms
  • Pharmacovigilance
  • Powder & Granules
  • Purchase Departments
  • Quality Assurance
  • Quality Control
  • Raw Material Stores
  • Regulatory Affairs
  • Tablet Manufacturing
  • Rectal Dosage Forms
  • Transdermal Patches
  • Vaginal Dosage Forms
  • Validations and Qualifications

Read SOPs in your Language:

 - 
Bengali
 - 
bn
English
 - 
en
Gujarati
 - 
gu
Hindi
 - 
hi
Malayalam
 - 
ml
Marathi
 - 
mr
Punjabi
 - 
pa
Tamil
 - 
ta
Telugu
 - 
te

NEW! Revised SOPs – V 2.0

  • Aerosols V 2.0
  • Analytical Method Development V 2.0
  • API Manufacturing V 2.0
  • BA-BE Studies V 2.0
  • Biosimilars V 2.0
  • Capsules V 2.0
  • Creams V 2.0
  • Elixers V 2.0
  • Ointments V 2.0
  • Raw Material Warehouse V 2.0
  • Tablet Manufacturing V2.0

New Publication: A must for All.

Copyright © 2025 SOP Guide for Pharma.

Powered by PressBook WordPress theme

Go to mobile version