Procedure to Prevent Material Handling Mix-Ups in Aerosol Manufacturing

1. Purpose

The purpose of this Standard Operating Procedure (SOP) is to establish a structured approach to preventing material mix-ups during handling in aerosol manufacturing. This ensures correct material usage, traceability, and compliance with Good Manufacturing Practices (GMP).

2. Scope

This SOP applies to all materials handled in the aerosol department, including raw materials, packaging components, labeling, and finished goods.

3. Responsibilities

• Warehouse Team: Responsible for correct receipt, storage, and issuance of materials.
• Production Team: Responsible for verifying materials before use.
• Quality Assurance (QA) Team: Responsible for conducting random checks and ensuring compliance.
• Material Handling Operators: Responsible for following material identification procedures.

4. Accountability

The Production Manager is accountable for ensuring that material mix-ups do not occur during handling.

5. Procedure

5.1. Material Identification and Labeling

1. All incoming materials must be clearly labeled with:
   • Material Name
   • Batch Number
   • Expiry Date
   • Storage Conditions
2. Ensure all materials have corresponding Material Identification Tags (Annexure-1).

5.2. Storage and Segregation

1. Store materials in designated areas based on:
   • Material Type (Active ingredients, Excipients, Packaging materials)
   • Batch Status (Approved, Quarantined, Rejected)
2. Maintain separate storage racks for different materials.
3. Record storage details in the Material Storage Log (Annexure-2).

5.3. Issuance and Verification

1. Before issuing materials for production:
   • Verify against