SOP Guide for Pharma

Aerosol: SOP for Label Verification During Aerosol Packing – V 2.0

Aerosol: SOP for Label Verification During Aerosol Packing – V 2.0

Procedure for Verifying Labels During Aerosol Packing

Department Aerosol
SOP No. SOP/Aerosol/178/2025
Supersedes SOP/Aerosol/178/2022
Page No. Page 1 of Y
Issue Date 06/02/2025
Effective Date 16/02/2025
Review Date 06/02/2028

1. Purpose

The purpose of this Standard Operating Procedure (SOP) is to establish a systematic process for verifying labels on aerosol products during packaging. Proper label verification ensures product identification, regulatory compliance, and prevention of labeling errors.

2. Scope

This SOP applies to all aerosol products undergoing label application and verification before packaging, ensuring correctness in batch details, expiry dates, barcodes, and product information.

3. Responsibilities

  • Packaging Operators: Responsible for verifying and applying labels accurately.
  • Quality Assurance (QA) Team: Responsible for performing periodic label verification checks.
  • Production Supervisor: Responsible for monitoring labeling operations and ensuring compliance.
  • Regulatory Affairs Team: Responsible for ensuring label content complies with regulatory requirements.

4. Accountability

The Packaging Manager is accountable for ensuring that labels on aerosol products meet regulatory and company standards.

5. Procedure

5.1. Pre-Labeling Verification

  1. Ensure that label artwork has been approved by Regulatory Affairs.
  2. Cross-check label specifications with the Label Specification Sheet (Annexure-1).
  3. Inspect the printing quality and clarity of labels.

5.2. Label Application Process

  1. Ensure the correct label roll is loaded into the label applicator.
  2. Verify the label alignment on the first five containers.
  3. Conduct routine checks every 30 minutes during production.
  4. Record label verification results in
the Label Verification Log (Annexure-2).

5.3. Barcode and Batch Code Verification

  1. Verify that the barcode scans correctly and matches the product database.
  2. Ensure batch coding includes:
    • Batch Number
    • Manufacturing Date
    • Expiry Date
  3. Record all findings in the Barcode and Batch Code Log (Annexure-3).

5.4. Handling Labeling Errors

  1. Identify incorrect or misaligned labels and remove defective units.
  2. Record labeling errors in the Label Error Log (Annexure-4).
  3. Investigate repeated errors and implement corrective actions.

5.5. Post-Labeling Verification

  1. Perform a final inspection on a random sample of labeled units.
  2. Ensure all labeled units are correctly placed in secondary packaging.
  3. QA personnel must approve and sign off on the Label Verification Checklist (Annexure-5).

6. Abbreviations

  • GMP: Good Manufacturing Practice
  • QA: Quality Assurance
  • SOP: Standard Operating Procedure
  • SKU: Stock Keeping Unit

7. Documents

  1. Label Specification Sheet (Annexure-1)
  2. Label Verification Log (Annexure-2)
  3. Barcode and Batch Code Log (Annexure-3)
  4. Label Error Log (Annexure-4)
  5. Label Verification Checklist (Annexure-5)

8. References

  • Good Manufacturing Practice (GMP) Guidelines
  • FDA Labeling Requirements for Aerosol Products
  • ISO 9001 – Quality Management Systems

9. SOP Version

Version: 2.0

10. Approval Section

Prepared By Checked By Approved By
Signature
Date
Name
Designation
Department

11. Annexures

Annexure-1: Label Specification Sheet

Product Name Label Dimensions Regulatory Approval
Aerosol Spray X 50 mm x 100 mm Approved

Annexure-2: Label Verification Log

Batch No. Verification Date Checked By Status
BN-123 07/02/2025 Ramesh Kumar Pass

Annexure-3: Barcode and Batch Code Log

Batch No. Barcode Scan Result Batch Code Correctness Verified By
BN-124 Scanned Successfully Correct Priya Sharma

Annexure-4: Label Error Log

Error Type Batch No. Occurrence Rate Corrective Action
Misaligned Label BN-125 1% Recalibrated label applicator

Annexure-5: Label Verification Checklist

Checklist Item Checked By Verification Date Status
Label Placement Amit Sharma 08/02/2025 Pass

12. Revision History:

Revision Date Revision No. Revision Details Reason for Revision Approved By
01/01/2024 V 1.0 Initial Release First Issue Anjali Sharma
01/01/2025 V 2.0 Updated label verification process GMP Compliance Anjali Sharma
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